Spotting while on testosterone. We analyzed transgender men undergoing gender-affirming hormone therapy (GAHT) with testosterone who experienced breakthrough bleeding in order to identify the factors associated with this condition. One-third of transgender and gender-diverse individuals on testosterone will experience at least one breakthrough bleeding episode, even after their first year of use, researchers reported in the Discussion: Transgender men and hormone-prescribing providers can be reassured that vaginal bleeding and spotting usually stop within 3 months after testosterone initiation. A menstrual cycle can be a source of gender dysphoria for some transgender men, but it is not dysphoric for all trans men. Struggling with unscheduled bleeding while on Hormone Replacement Therapy (HRT)? Discover the causes, when to seek help, and how to manage it effectively. Other causes of bleeding after menopause can include: Thinning of the tissue lining the vagina and uterus due to less A third of individuals experienced breakthrough bleeding after the initial year of testosterone use, and the majority who bled did so by the end of their second year on testosterone and while on consistent dosing with serum testosterone levels in the target range. Inadequate testosterone levels can cause problem bleeding and we would recommend checking Testosterone levels at the appropriate time. With time, the right balance of hormones, and support from your doctor, it often settles - leaving you free to focus on feeling better. Breakthrough bleeding can worsen dysphoria and patients may seek management to reattain amenorrhea. If vaginal bleeding persisted, starting progestogens at three months resulted in a decrease in the intensity of vaginal bleeding and spotting. If you have been on testosterone for a while and your period came back unexpectedly it is best to consult a doctor. If you have been period-free while taking testosterone and you suddenly start experiencing bleeding again, please see your healthcare provider for a checkup. Often, the bleeding stops within six months. g. Because of this, there is a need to assess efficacy of management approaches. We normally recommend trough level (immediately before injection or if not possible within two days prior to injection) on Sustanon/ Enanthate; mid-way between injections on Nebido (although can be a trough sample of logistically easier); 4 to 6 hours after Feb 13, 2024 · This article explores why some individuals may experience heavy bleeding while undergoing testosterone hormone therapy and discusses possible causes, management strategies, and when to seek medical advice. However, breakthrough bleeding is not uncommon, even after years of using testosterone. Factors associated with vaginal bleeding or spotting included lower serum testosterone levels and being on testosterone gel as compared to injections (e. But if your bleeding concerns you, talk with your healthcare professional. While many people find their periods stop soon after they start testosterone, others find that their periods don’t stop, or that they stop and start intermittently. Dec 1, 2025 · Spotting while on HRT can be frustrating, but in many cases it’s a normal sign that your body is adjusting. , esters or undecanoate preparations). Changes to the endometrium (the lining of the uterus) vary, and no major changes appear to occur in the ovaries. . Menopause hormone therapy can result in light bleeding or bleeding that's as heavy as a typical period. In response to the significant increase in women presenting with unscheduled bleeding on HRT, the British Menopause Society, in partnership with the British Society of Gynaecological Endoscopy, British Gynaecological Cancer Society, Faculty of Sexual & Reproductive Healthcare, Getting It Right First Time (GIRFT) and the Royal College of Obstetricians & Gynaecologists, has produced a Purpose While it is common for menstrual cycles to cease within the initial 6 months of treatment, there are instances where some transgender men may not experience this cessation. Methods In this For those who had periods prior to starting testosterone, regular bleeding typically stops within the first six months of hormone therapy. Feb 12, 2020 · Factors associated with vaginal bleeding or spotting included lower serum testosterone levels and being on testosterone gel as compared to injections (e. A sudden return of periods in a person on testosterone could indicate a health problem, or it could be a benign change. Sep 22, 2025 · Experiencing testosterone postmenopausal bleeding? Learn from board-certified gynecologist Jennifer Davis about the potential link between testosterone therapy and postmenopausal bleeding, other causes, diagnostic steps, and crucial advice for women navigating menopause. Nov 14, 2024 · One of the commonly desired effects of testosterone gender-affirming hormone therapy (GAHT) is that it usually stops menstrual periods. If not, serum testosterone levels should be measured and testosterone dose adjusted to achieve serum testosterone levels in the physiologic male range. While many transgender and gender diverse individuals rapidly achieve amenorrhea on testosterone, emerging data have identified that breakthrough bleeding can occur in up to one-third of individuals with long-term use. Secondary aims included identifying the time to first bleed for those who experienced breakthrough bleeding and the risk factors associated with breakthrough bleeding while on testosterone therapy. Get expert insights on managing this important health concern. 4lu9, 6d6g, th2x, tf8o, egfxe, wdlw, bykc2a, bfs5e, lgoi, po1y6,